Potential of kidney cell cultures from nonhibernating thirteen-lined ground squirrels (Citellus tridecemlineatus) for virus propagation.

Experimental Infection of Ground Squirrels (Spermophilus tridecemlineatus) with Monkeypox Virus

A proposed new small-animal (rodent) model for studying the pathogenesis and treatment of severe orthopoxvirus infections is described. Thirteen-lined ground squirrels (Spermophilus tridecemlineatus) were infected intraperitoneally and intranasally with monkeypox virus (MPXV). A fulminant illness developed in all animals, and they died 6-9 days after infection. Virus was cultured from the blood...

Analysis of four common play patterns in juvenile thirteen-lined ground squirrels (Spermophilus tridecemlineatus)

Effect of hypothalamic lesions on temperature regulation in hibernating ground squirrels.

The evidence for the importance of the hypothalamus in hibernationin mammals was reviewed recently by Mrosovsky 3. The role played by anterior hypothalamic and preoptic areas in the regulation of body temperature in non-hibernators is well known; a few studies seem to indicate that these areas are important in hibernators as well. Satinoff4, 5 found that ground squirrels, made hypothermic by hy...

Noninvasive imaging of the thirteen-lined ground squirrel photoreceptor mosaic.

Ground squirrels are an increasingly important model for studying visual processing, retinal circuitry, and cone photoreceptor function. Here, we demonstrate that the photoreceptor mosaic can be longitudinally imaged noninvasively in the 13-lined ground squirrel (Ictidomys tridecemlineatus) using confocal and nonconfocal split-detection adaptive optics scanning ophthalmoscopy using 790 nm light...

Effect of cooling on vascular smooth muscle from the thirteen-lined ground squirrel.

Peripheral vascular resistance in the ground squirrel (Spermophilus tridecemlineatus) increases when the animal enters hibernation. The goals of this study were to determine if a change in vascular reactivity contributes to this hemodynamic response, and to compare the effects of temperature on vascular responsiveness in a hibernator (ground squirrel) and a nonhibernating mammal (rat). Helicall...